Vincent PELLAS
Expertise
- Core-shell nanoparticles
- Colloidal synthesis
- Surface Functionalization
- Bioapplications
PHD SUBJECT
Elaboration of silica coated gold nanorods (AuNR@SiO2) – Towards versatile nanoplatforms for biomedical applications
SUMMARY
Core shell AuNR@SiO2 nanorods are hybrid nanocomposites of great interest for their use In bioimaging, targeted drug delivery, photothermal therapy and biosensing. Silica as an outer shell coating material is known to improve the colloidal and thermal stability while sustaining the optical properties of the core. It can then be used as a nanoplatform for further functionalization or bioconjugation.
We envision in this project two applications of the core-shell material: in one hand the development of an efficient colorimetric biosensor for life style monitoring including detection of toxins in complex media. A thin silica shell will preserve the LSPR sensitivity to local changes in refractive index of the media. On the other hand AuNR with controlled silica thickness and pore organization will be used to encapsulate therapeutic agents which release can be triggered upon infrared irradiation in photothermal therapies
TEM images of Silica coated gold nanorods with different silica thickness and pore organization
Characterization techniques
UV-Vis, IR, Raman spectroscopies, DLS, Zêta potential, TGA, TEM and SEM.
Contact Informations
Mail(s) : vincent.pellas@upmc.fr
Function and attachment
PhD. Candidate
Also in the section
08.04.2021 - 08.04.2021
David Hu - Thesis defense
Congratulations to David for his PhD defense and for his incredible work on Nanocomposites Photocatalysts UCNP@SiO2@ZnO, active under NIR light for wastewater treatment", performed under the supervision of Juliette Blanchard and Souhir Boujday.
06.04.2021 - 06.04.2021
Valentin's arrival
Warm welcome to Valentin for his 3 months Master 1 internship on the "Adsorption of thiolate molecules on gold surfaces" under the supervision of Souhir Boujday and Yacine Mazouzi.
15.03.2021 - 15.03.2021
Thesis Defense - Somia Tomane
Congratulations to Somia Tomane for her thesis defense and for her work on the "Synthesis and characterization of polyoxometallate/mettalic nanoparticles composites for biomedical applications", a work performed in the Institut Lavoisier de Versailles and within our group, under the supervision of Pierre Mialane, Anne Dolbecq, Anne Vallée and Souhir Boujday.