Go to content Go to the menu Go to the search

Vincent PELLAS

Expertise

  • Core-shell nanoparticles
  • Colloidal synthesis
  • Surface Functionalization
  • Bioapplications

PHD SUBJECT

Elaboration of silica coated gold nanorods (AuNR@SiO2) – Towards versatile nanoplatforms for biomedical applications

SUMMARY

Core shell AuNR@SiO2 nanorods are hybrid nanocomposites of great interest for their use In bioimaging, targeted drug delivery, photothermal therapy and biosensing. Silica as an outer shell coating material is known to improve the colloidal and thermal stability while sustaining the optical properties of the core. It can then be used as a nanoplatform for further functionalization or bioconjugation.

We envision in this project two applications of the core-shell material: in one hand the development of an efficient colorimetric biosensor for life style monitoring including detection of toxins in complex media. A thin silica shell will preserve the LSPR sensitivity to local changes in refractive index of the media. On the other hand AuNR with controlled silica thickness and pore organization will be used to encapsulate therapeutic agents which release can be triggered upon infrared irradiation in photothermal therapies

 
TEM images of Silica coated gold nanorods with different silica thickness and pore organization

 

Characterization techniques

UV-Vis, IR, Raman spectroscopies, DLS, Zêta potential, TGA, TEM and SEM.

Contact Informations

Mail(s) : vincent.pellas@upmc.fr

Function and attachment

PhD. Candidate

27/11/19

Traductions :
      • French Electron Spectroscopy Workshop

        The third edition of the French Electron Spectroscopy Workshop was held in Paris on January 21st-22nd, 2020. Organized by the French Vacuum Society, once again the workshop was in close partnership with the Condensed Matter Division of the French Physical Society and in collaboration with the Surfaces and Interfaces Workshop.

        Yacine presented one of his Ph.D. projects entitled: " Contribution of X-ray...

      • Sunny


        SunYoung Hur
         
        Sunny, PhD student in cotutelle with NTU Singapore, has joined our group for a year. Warm welcome!

      • Mona

        Mona SOroush
         
        Mona Soroush, PhD student from Teheran University has joined our group. Warm welcome!