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Naked-Eye Biosensing using Plasmonic Nanoparticles

Since the introduction of LSPR as a transduction technique, monitoring the antibody/antigen is only possible by UV-Visible spectroscopy. Indeed, the color changes resulting from a displacement of the LSPR band during target recognition are, for spherical gold nanoparticles that often absorb around 520 nm, a few nanometers and are therefore not visible to the naked eye. Indeed, in this region of the electromagnetic spectrum, red extends over several tens of nm. A plasmon band located slightly lower in the electromagnetic spectrum would generate a much more noticeable colour change for an equivalent displacement. The combination of gold and silver in the form of an alloy or core-shell allows the position of the LSPR band to be modulated and located in the area of interest.

08/11/19

Traductions :
      • Or-Nano You-Tube conferences

        A compact 20 min Conference on the couple Antibody/Gold Nanoparticles in the framework of "les conférences digitales Or-Nano", Nice exercice!
        Thanks to the Gdr Or-Nano for the invitation and the sharing ;)
        Below the abstract and the link to the conference
        https://youtu.be/3gGCOopVasc

        http://or-nano.insp.upmc.fr/conference-digitale-2020.html?L=692

      • Literature review in Biosensors & Bioelectronics on AuNP-Ab Bioconjugates

        How to attach an antibody to AuNP? What strategies and what efficiency? How many Ab can one AuNP accomodate?
        Find some answers to these questions in our literature Review just accepted in Biosensors & Biolectronics tackling Antibody-Gold nanoparticle Bioconjugates for Biosensors applications

      • Webinar at the Tunisian Chemical Society

        Facing the confinement during COVID19 pandemic crisis most conferences switched to webinar, below a link to watch the invited conference on plasmonic nanoparticles for optical Biosensing (in French!)
        http://www.sctunisie.org/webinar20/
        https://drive.google.com/file/d/11j7yK7Dh1vtxIhctmiZ4xGvLliurfBa5/view