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Zihua Yang

Expertise

  • Surface functionalization & characterization 
  • Metallic Nanoparticles synthesis & characterization 
  • Localized Surface Plasmon Resonance (LSPR) biosensors
  • Silica coating

Techniques 

  • UV-VIS spectroscopy 
  • DLS 
  • QCM-D 
  • IR 
  • TEM/SEM microscopies 
  • XPS 

PhD. subject 

Plasmonic nanoparticles for biosensing and therapy 

Summary 

Noble metal nanoparticles display fascinating properties mainly owing to their optical features resulting from the localized surface plasmon resonance (LSPR) effect. They absorb and / or scatter light in the visible to the NIR spectral region, depending on their size, shape, composition and state of surface. Any change of these parameters will result in a shift of the LSPR band position that may in turn result in a dramatic change of color, depending on the magnitude of the shift.

Several years ago, we have initiated research projects dealing with the use of noble metal nanoparticles for analytical purposes. For instance, we set up several metal nanoparticle-based biosensors to detect and quantify Enterotoxin A from Staphylococcus aureus (SEA), a biotoxin responsible for food intoxications. A solution phase, homogeneous assay was designed in which binding of SEA to antibody-gold nanoparticle bioconjugate resulted in a red shift of the LSPR band owing to the change of refractive index at the vicinity of the metal nanoparticles (Au or core-shell Au-Ag).

Function and attachment

PhD. candidate

22/01/21

Traductions :
      • David Hu - Thesis defense

        Congratulations to David for his PhD defense and for his incredible work on Nanocomposites Photocatalysts UCNP@SiO2@ZnO, active under NIR light for wastewater treatment", performed under the supervision of Juliette Blanchard and Souhir Boujday. 

      • Valentin's arrival

        Warm welcome to Valentin for his 3 months Master 1 internship on the "Adsorption of thiolate molecules on gold surfaces" under the supervision of Souhir Boujday and Yacine Mazouzi. 

      • Thesis Defense - Somia Tomane

        Congratulations to Somia Tomane for her thesis defense and for her work on the "Synthesis and characterization of polyoxometallate/mettalic nanoparticles composites for biomedical applications", a work performed in the Institut Lavoisier de Versailles and within our group, under the supervision of Pierre Mialane, Anne Dolbecq, Anne Vallée and Souhir Boujday.