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Alexis LOISEAU

Expertise

My research activities are focused on the synthesis (titanate nanotubes, gold and silver nanoparticles, gold-silver core-shells, gold nanoshells), characterization and functionalization of nanomaterials for biomedical applications, especially in nanomedicine and biosensor areas.

Analysis techniques

TGA – z-potential – DLS – XPS – TEM– IR/UV/Raman – LSPR – QCM-D

Softwares

TRIOS – Zetasizer/AntonParr – Casa XPS – MultiPak – DigitalMicrograph – ImageJ – OPUS – UV-Probe – Qsoft/Qtools – Insplorer – Endnote – Office – Origin 

Function and attachment

Post-Doctoral Researcher

Career

  • April 2018 – July 2019

Laboratory LRS, Sorbonne University (Paris, France) | Postdoctoral position « Gold-based plasmonic biosensors for small-sized analytes », French-Austrian ANR-FWF program: NanoBioSensor. Successful management of two Master students (five months)

  • 2014 – 2017

Laboratory ICB, Nanosciences Department, (Bio)-Hybrid Nanoparticles & Nanostructures, University of Burgundy (Dijon, France) | PhD in Physical-Chemistry « Titanate nanotubes as versatile nanovectors: radiosensitizers for the treatment of prostate cancer and nuclear imaging probes » in partnership with the Centre Georges François Leclerc, cancer centre of Burgundy (Dijon, France) and the UTINAM Institute at the University of Franche-Comté (Besançon, France). Thesis defense: 15th November 2017

Publications

  • Titanate Nanotubes Engineered with Gold Nanoparticles and Docetaxel to Enhance Radiotherapy on Xenografted Prostate Tumors, A. Loiseau, J. Boudon, A. Oudot, M. Moreau, R. Boidot, R. Chassagnon, N. M. Saïd, S. Roux, C. Mirjolet, N. Millot, Cancers, 11(12), 1962 (2019), doi:10.3390/cancers11121962.
  • Core-shell gold silver nanoparticles for LSPR-based naked-eye toxin biosensing, A. Loiseau, L. Zhang, D. Hu, M. Salmain, Y. Mazouzi, R. Flack, B. Liedberg, S. Boujday, ACS Applied Materials & Interfaces, 11(50), 46462-46471 (2019), doi:10.1021/acsami.9b14980.
  • Silver-based plasmonic nanoparticles for and their use in biosensing, A. Loiseau, V. Asila, G. Boitel-Aullen, M. Lam, M. Salmain, S. Boujday, Biosensors, 9(2), 78 (2019), doi:10.3390/bios9020078 (Review).
  • Spatially controlled reduction and growth of silver in hollow gold nanoshell particles, L. Zhang, P. Chen, A. Loiseau, D. Brouri, S. Casale, M. Salmain, S. Boujday, B. Liedberg, Journal of physical Chemistry C, 123, 10614-10621 (2019), doi:10.1021/acs.jpcc.8b11864 (Cover).
  • In vitro interaction and biocompatibility of titanate nanotubes with microglial cells, S. Sruthi, A. Loiseau, J. Boudon, F. Sallem, L. Maurizi, P.V. Mohanan, G. Lizard, N. Millot, Toxicology and Applied Pharmacology, 353, 74-86 (2018), doi:10.1016/j.taap.2018.06.013.
  • Taxane-grafted metal-oxide nanoparticles as a new theranostic tool against cancer: The promising example of docetaxel-functionalized titanate nanotubes on prostate tumors, A. Loiseau, J. Boudon, C. Mirjolet, G. Créhange, N. Millot, Advanced Healthcare Materials, 6, 1700245 (2017), doi:10.1002/adhm.201700245.
  • Docetaxel-titanate nanotubes enhance radiosensitivity in an androgen-independent prostate cancer model, C. Mirjolet, J. Boudon, A. Loiseau, S. Chevrier, R. Boidot, A. Oudot, B. Collin, N. Millot, G. Créhange, International Journal of Nanomedicine, 12, 6357 (2017), doi:10.2147/IJN.S139167.
  • Dispersion of titanate nanotubes for nanomedicine: comparison of PEI and PEG nanohybrids, A.L. Papa, J. Boudon, V. Bellat, A. Loiseau, F. Sallem, R. Chassagnon, V. Bérard, N. Millot, Dalton Transactions, 44, 739-746 (2015), doi:10.1039/c4dt02552k

06/01/20

Traductions :
      • David Hu - Thesis defense

        Congratulations to David for his PhD defense and for his incredible work on Nanocomposites Photocatalysts UCNP@SiO2@ZnO, active under NIR light for wastewater treatment", performed under the supervision of Juliette Blanchard and Souhir Boujday. 

      • Valentin's arrival

        Warm welcome to Valentin for his 3 months Master 1 internship on the "Adsorption of thiolate molecules on gold surfaces" under the supervision of Souhir Boujday and Yacine Mazouzi. 

      • Thesis Defense - Somia Tomane

        Congratulations to Somia Tomane for her thesis defense and for her work on the "Synthesis and characterization of polyoxometallate/mettalic nanoparticles composites for biomedical applications", a work performed in the Institut Lavoisier de Versailles and within our group, under the supervision of Pierre Mialane, Anne Dolbecq, Anne Vallée and Souhir Boujday.