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Médéric LEQUEUX

Expertise

  • Gold Nanostructures
  • SERS
  • Plasmonic
  • QCM-D
  • Molecular interaction
  • Biosensor
PhD. Subject

Biodetection of small analytes with resonant nanostructures

This project is based on ANR project named Nanobiosensor, have for goal to make a QCM/SERS biosensor to sense small analytes. Development of transducer with nanostructures allow to obtain a better reproducibility and measurement reliability. Gold nanostructures allow me to acquire SERS measurement of molecule on the surface and identify it. Moreover, the nanostructures on quartz ship allow me to quantify how many molecules I have on the surface. The coupling of QCM/SERS allow me the access of identification, quantity and observation of small analyte.

This coupling has two main goal, the first is to improve the understanding of molecular interaction between streptomycin and the bioreceptor. And the second, the coupling of these two methods allow to develop a sensor to detect small analytes.

Characterization techniques

Raman spectroscopy, QCM-D, MEB, AFM

Function and attachment

PhD. Candidate

27/11/19

Traductions :
      • Or-Nano You-Tube conferences

        A compact 20 min Conference on the couple Antibody/Gold Nanoparticles in the framework of "les conférences digitales Or-Nano", Nice exercice!
        Thanks to the Gdr Or-Nano for the invitation and the sharing ;)
        Below the abstract and the link to the conference
        https://youtu.be/3gGCOopVasc

        http://or-nano.insp.upmc.fr/conference-digitale-2020.html?L=692

      • Literature review in Biosensors & Bioelectronics on AuNP-Ab Bioconjugates

        How to attach an antibody to AuNP? What strategies and what efficiency? How many Ab can one AuNP accomodate?
        Find some answers to these questions in our literature Review just accepted in Biosensors & Biolectronics tackling Antibody-Gold nanoparticle Bioconjugates for Biosensors applications

      • Webinar at the Tunisian Chemical Society

        Facing the confinement during COVID19 pandemic crisis most conferences switched to webinar, below a link to watch the invited conference on plasmonic nanoparticles for optical Biosensing (in French!)
        http://www.sctunisie.org/webinar20/
        https://drive.google.com/file/d/11j7yK7Dh1vtxIhctmiZ4xGvLliurfBa5/view