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Médéric LEQUEUX

Expertise

  • Gold Nanostructures
  • SERS
  • Plasmonic
  • QCM-D
  • Molecular interaction
  • Biosensor
PhD. Subject

Biodetection of small analytes with resonant nanostructures

This project is based on ANR project named Nanobiosensor, have for goal to make a QCM/SERS biosensor to sense small analytes. Development of transducer with nanostructures allow to obtain a better reproducibility and measurement reliability. Gold nanostructures allow me to acquire SERS measurement of molecule on the surface and identify it. Moreover, the nanostructures on quartz ship allow me to quantify how many molecules I have on the surface. The coupling of QCM/SERS allow me the access of identification, quantity and observation of small analyte.

This coupling has two main goal, the first is to improve the understanding of molecular interaction between streptomycin and the bioreceptor. And the second, the coupling of these two methods allow to develop a sensor to detect small analytes.

Characterization techniques

Raman spectroscopy, QCM-D, MEB, AFM

Function and attachment

PhD. Candidate

27/11/19

Traductions :
      • Title story on the front page of Biosensors

        Our review on gold nanorods title story on the front page of Biosensors
        https://www.linkedin.com/feed/update/urn:li:activity:6732242466830917632/

      • Article in Nanomaterials

        Our work " Nanostructured and Spiky Gold Shell Growth on Magnetic Particles for SERS Applications ", is now published in Nanomaterials

        link: https://doi.org/10.3390/nano10112136

      • Literature review on Gold Nanorods in Biosensors

        Check our up-to-date overview of gold nanorods in LSPR biosensing. We start from synthesis and coating with a silica shell of controlled thickness and porosity, then, we discuss surface functionalization to attach various bioreceptors and finally, we review AuNR-based LSPR biosensors and their analytical performances.