Médéric LEQUEUX

Expertise

• Gold Nanostructures
• SERS
• Plasmonic
• QCM-D
• Molecular interaction
• Biosensor

PhD. Subject

Biodetection of small analytes with resonant nanostructures

This project is based on ANR project named Nanobiosensor, have for goal to make a QCM/SERS biosensor to sense small analytes. Development of transducer with nanostructures allow to obtain a better reproducibility and measurement reliability. Gold nanostructures allow me to acquire SERS measurement of molecule on the surface and identify it. Moreover, the nanostructures on quartz ship allow me to quantify how many molecules I have on the surface. The coupling of QCM/SERS allow me the access of identification, quantity and observation of small analyte.

This coupling has two main goal, the first is to improve the understanding of molecular interaction between streptomycin and the bioreceptor. And the second, the coupling of these two methods allow to develop a sensor to detect small analytes.

Characterization techniques

Raman spectroscopy, QCM-D, MEB, AFM